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Jonathan Kahn: Race in a Bottle : The Story of BiDil and Racialized Medicine in a Post-Genomic Age

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At a ceremony announcing the completion of the first draft of the human genome in 2000, President Bill Clinton declared, "I believe one of the great truths to emerge from this triumphant expedition inside the human genome is that in genetic terms, all human beings, regardless of race, are more than 99.9 percent the same." Yet despite this declaration of unity, biomedical research has focused increasingly on mapping that.1 percent of difference, particularly as it relates to race.This trend is exemplified by the drug BiDil. Approved by the FDA in 2005 as the first drug with a race-specific indication on its label, BiDil was originally touted as a pathbreaking therapy to treat heart failure in black patients and help underserved populations. Upon closer examination, however, Jonathan Kahn reveals a far more complex story. At the most basic level, BiDil became racial through legal maneuvering and commercial pressure as much as through medical understandings of how the drug worked. Using BiDil as a central case study, Kahn broadly examines the legal and commercial imperatives driving the expanding role of race in biomedicine, even as scientific advances in genomics could render the issue irrelevant. He surveys the distinct politics informing the use of race in medicine and the very real health disparities caused by racism and social injustice that are now being cast as a mere function of genetic difference. Calling for a more reasoned approach to using race in biomedical research and practice, Kahn asks readers to recognize that, just as genetics is a complex field requiring sensitivity and expertise, so too is race, particularly in the field of biomedicine.

Ansel Adams produced some of the century's truly memorable photographic images and helped nurture the art of photography through his creative innovations and peerless technical mastery. This handbook - the first volume in Adam's celebrated series of books on photographic techniques - has taught a generation of photographers how to harness the camera's artistic potential. It remains as vital today as when it was first published. Along with visualization, image management, Adams' famous Zone System, and other keys to photographic artistry, The Camera covers 35mm, medium-format, and large-format view cameras and offers detailed advice on camera components such as lenses, shutters, and light meters. Beautifully illustrated Race in a Bottle : The Story of BiDil and Racialized Medicine in a Post-Genomic Age free download pdf with photographs as well as instructive line drawings, this classic manual belongs on every serious photographer's bookshelf.

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Peter Coleman,Ann O Hanlon: Ageing and Development

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With increasing numbers of the population living into old age, we need a better understanding of the nature and experience of ageing in all its aspects. Up to now, very few texts have considered this in any depth, but 'Ageing and Development', a new volume in the Texts in Developmental Psychology series, provides a detailed and comprehensive overview of the theories and research in adult development into old age. The classic early accounts of theorists such as Jung and Erikson are considered, as well as their present day successors. Particular attention is given to theories of adjustment to loss, and to the threat of loss, which dominate current gerontological research. A notable feature of the book is the separate section devoted to the psychology of advanced old age, to life in states of physical and/or mental frailty, and to the survival of the self in these circumstances. There is a strong emphasis throughout on up-to-date empirical research and illustrative case examples. The reader is constantly encouraged to take a critical perspective, to understand the strengths and limitations of different studies, and to think about the issues raised in terms of their own lives.

A major and controversial new biography of one of the most compelling and contradictory figures in modern British life. Born Alexander Boris de Pfeffel Johnson, to most of us he is just 'Boris' - the only politician of the age to be regarded in such familiar, even affectionate terms. Uniquely, he combines comedy with erudition, gimleteyed focus with jokey self-deprecation, and is a loving family man with a roving eye. He is also a hugely ambitious figure with seemingly no huge ambitions to pursue - other than, perhaps, power itself. One of the most private men in public life, we all know of Boris, but so few can truly claim to know him. He invites attention, but has evaded scrutiny. Now, from Living Cities in Japan: Citizens' Movements, Machizukuri and Local Environments download book the vantage point of a once close colleague, Sonia Purnell charts his remarkable rise and offers the first forensic account of just how he did it.

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James Patterson: Cross Country

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Detective Alex Cross pursues the most ruthless killer he's ever encountered-to a land of sheer terror and back. It's the worst crime scene Alex Cross has ever seen, and then more killings, each one more ruthless than the last, quickly follow. After one death comes terrifyingly close to home, Alex realizes he's chasing a horrible new breed of killer. Digging deeper into the case, Alex and his girlfriend, Detective Brianna Stone, uncover a shocking Washington, D.C., underworld: a gang of teenage thugs headed by a warlord known only as the Tiger. When the Tiger's elusive trail turns up in Africa, Alex knows that he must follow. Unprotected and alone, can Alex manage to both survive and catch the killer?

Adding some 20 percent to the original content, this is a completely updated edition of the indispensable guide to Thomas Pynchon's "Gravity's Rainbow". Steven Weisenburger takes the reader page by page, often line by line, through the welter of historical references, scientific data, Cross Country ebook pdf cultural fragments, anthropological research, jokes, and puns around which Pynchon wove his story. Weisenburger fully annotates Pynchon's use of languages ranging from Russian and Hebrew to such subdialects of English as 1940s street talk, drug lingo, and military slang as well as the more obscure terminology of black magic, Rosicrucianism, and Pavlovian psychology. The Companion also reveals the underlying organization of "Gravity's Rainbow" - how the book's myriad references form patterns of meaning and structure that have eluded both admirers and critics of the novel. The Companion is keyed to the pages of the principal American editions of "Gravity's Rainbow": Viking/Penguin (1973), Bantam (1974), and the special, repaginated Penguin paperback (2000) honoring the novel as one of twenty "Great Books of the Twentieth Century."

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Roger Goodman,Yuki Imoto,Tuukka Toivonen: A Sociology of Japanese Youth: From Returnees to NEETs

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Over the past thirty years, whilst Japan has produced a diverse set of youth cultures which have had a major impact on popular culture across the globe, it has also developed a succession of youth problems which have led to major concerns within the country itself. Drawing on detailed empirical fieldwork, the authors of this volume set these issues in a clearly articulated 'social constructionist' framework, and put forth a sociology of Japanese youth problems which argues that there is a certain predictability about the way in which these problems are discovered, defined and dealt with. The chapters include case studies covering issues such as: Returnee children (kikokushijo) Compensated dating (enjo kosai) Corporal punishment (taibatsu) Bullying (ijime) Child abuse (jido gyakutai) The withdrawn youth (hikikomori) and NEETs (not in education, employment or training) By examining these various social problems collectively, A Sociology of Japanese Youth explains why particular youth problems appeared when they did and what lessons they can provide for the study of youth problems in other societies. This book will be of huge interest to students and scholars of Japanese society and culture, the sociology of Japan, Japanese anthropology and the comparative sociology of youth studies.

The book also treats the theological implications of contemporary science and evaluates recent approaches such as environmentalism, Then Comes Seduction ebook pdf gender studies, social construction, and postmodernism, which are at the center of current debates in the historiography, understanding, and application of science. Contributors: Colin A. Russell, David B. Wilson, Edward Grant, David C. Lindberg, Alnoor Dhanani, Owen Gingerich, Richard J. Blackwell, Edward B. Davis, Michael P. Winship, John Henry, Margaret J. Osler, Richard S. Westfall, John Hedley Brooke, Nicolaas A. Rupke, Peter M. Hess, James Moore, Peter J. Bowler, Ronald L. Numbers, Steven J. Harris, Mark A. Noll, Edward J. Larson, Richard Olson, Craig Sean McConnell, Robin Collins, William A. Dembski, David N. Livingstone, Sara Miles, and Stephen P. Weldon.

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Oscar Wilde,Robert Mighall: The Picture of Dorian Gray

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Part of Penguin's beautiful hardback Clothbound Classics series, designed by the award-winning Coralie Bickford-Smith, these delectable and collectible editions are bound in high-quality colourful, tactile cloth with foil stamped into the design. Enthralled by his own exquisite portrait, Dorian Gray exchanges his soul for eternal youth and beauty. Influenced by his friend Lord Henry Wotton, he is drawn into a corrupt double life; indulging his desires in secret while remaining a gentleman in the eyes of polite society. Only his portrait bears the traces of his decadence. The novel was a succes de scandale and the book was later used as evidence against Wilde at the Old Bailey in 1895. It has lost none of its power to fascinate and disturb.

Traveling to the darkest corners of our dining habits, Foer raises the unspoken question behind every fish we eat, every chicken we fry, and every burger we grill. Part memoir and part investigative report, "Eating Animals" is a book that, in the words of the "Los Angeles The Picture of Dorian Gray free pdf Times," places Jonathan Safran Foer "at the table with our greatest philosophers." A powerful, compulsively page-turning, vivid, and moving tribute to the experience of war and PTSD,The White Donkey tells the story of Abe, a young Marine recruit who experiences the ugly, pedestrian, and often meaningless side of military service in rural Iraq. He enlists in hopes of finding that missingsomething in his life but comes to find out that it's not quite what he expected. Abe gets more than he bargained for when his journey takes him to the middle east in war-torn Iraq. This is a story about a Marine, written and illustrated by a Marine, and is the first graphic novel about the war in Iraq from a veteran. The White Donkeyexplores the experience of being a Marine, as well as the challenges that veterans face upon their return home, and its raw power will leave you in awe.

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Jonathan Franzen: Freedom: A Novel

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In his first novel since The Corrections, Jonathan Franzen has given us an epic of contemporary love and marriage. FREEDOM comically and tragically captures the temptations and burdens of liberty: the thrills of teenage lust, the shaken compromises of middle age, the wages of suburban sprawl, the heavy weight of empire. In charting the mistakes and joys of FREEDOM's intensely realized characters as they struggle to learn how to live in an ever more confusing world, Franzen has produced an indelible and deeply moving portrait of our time.

The millennia-old history of Faerun is haunted with ghosts, vampires, zombies, and all other manner of gruesome undead. This anthology of all new stories is filled with the twelve most terrifying and lethal of these tales. From ancient lich kings to freshly turned ghouls; from disembodied hands to unholy, decaying angels, the dead in the Forgotten Realms(R) rarely rest in peace. On Coruscant, Luke and Mara Jade Skywalker have Freedom: A Novel download ebook pdf made a shocking discovery that is preventing the Yuuzhan Vong from exerting complete control. But when the enemy tracks them down, Luke and Mara are thrust into a fierce battle for their lives. Suddenly, the chances of escaping appear nearly impossible. And in space, another battle rages, one that holds ominous consequences for the New Republic--and for the Jedi themselves. . . .

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Sue Mongredien,Maria Pearson: Whale Rescue

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Molly returns to the Undersea Kingdom to help Animal-Keeper mermaid Leila find the missing whales. When they investigate they find the whales trapped inside a lobster pot but before they can set the whales free Molly and Leila are attacked by the Dark Queen's menacing mud monsters.

"Yaggoo" The launch of Sputnik in 1957 not only began the space age, it also showed that Soviet rockets were more powerful than American ones. Within months, the US Air Force hired Rocketdyne for a feasibility study of an engine capable of delivering at least 1 million pounds of thrust. Later, NASA ran the development of this F-1 engine in order to use it to power the first stage of the Saturn V rocket that would send Apollo missions to the Moon. It is no exaggeration to say that without the F-1 engine NASA would not have been able to achieve President Kennedy's 1961 challenge to his nation to land a man on the Moon before the decade was out. `You can't touch me,` I whisper. When Mitchell is released from prison after serving three years for a vicious attack he doesn't remember, he reluctantly finds himself caught up with Robert Gant, a ruthless lowlife with violent plans. Attempting to stay out of Gant's way, Mitchell finds work as a handyman at the mansion of a faded movie actress. When she eagerly plies him with cash, cars and sex, Mitch starts to wonder if even this Whale Rescue free epub job comes with a catch. But it isn't long before Mitchell's violent past catches up with him. When people close to him start getting hurt, Mitchell is forced to act, and take brutal on revenge on those who've stolen his life...

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Richard Molesworth: Wiped! Doctor Who's Missing Episodes

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Department of Defense: Special Operations Forces Medical Handbook

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The newest edition of the "Special Operations Forces Medical Handbook" is perfect and practical for both soldiers and civilians. Nearly 140 comprehensive illustrations show the proper techniques for medical care, from basic first-aid and orthopedics to instructions for emergency war surgery and even veterinary medicine. Questions are listed so that the medic can obtain an accurate patient history and perform a complete physical examination. Diagnoses are made easier with information on the distinctive features of each illness. This straightforward manual is sure to assist any reader faced with a medical issue or emergency. It features 139 black-and-white illustrations.

The SS was one of the most important institutions of Third Reich Germany, yet it is also among the least well understood. From the end of 1935, the SS had control over all police and internal security duties in Germany and the militarised Waffen SS had more than eight hundred thousand men serving in the field, in direct rivalry with the traditional German armed forces, the Wehrmacht. Making use of material not previously available, this definitive book refocuses attention on and enhances understanding of the hard-nosed political fanatics and opportunists who were responsible for one of the most appalling crimes in human history, the attempted execution of the Jews of Europe. For preschoolers a first lesson in finding your place in God s creation. his simple, beautiful book helps Special Operations Forces Medical Handbook pdf parents and children explore spirituality together by inviting children of all faiths and backgrounds to encounter God through everyday experience and the imagination. God s Paintbrush," playful text and lively illustrations guide very young children in finding faith through colors, song and dance. Preschoolers will delight in turning the sturdy pages and beginning the journey of finding joy and meaning in their world.

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Angela McAllister,Grahame Baker-Smith: Leon and the Place Between

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Wanting to prove to his brothers and sister that magic really exists, Leon volunteers to be in Abdul Kazam's magic show and gets transported to a mysterious world. Filled with rabbits, doves, playing cards and magician's assistants - among other things - if a magician can make it disappear, it will end up in the Place Between! When Leon returns, not only do his brothers and sister believe, but we do too. With diecut holes into and out of the Place Between, the reader takes a journey right through the pages of the book, into the mysterious world of Grahame Baker-Smith's breath-taking illustrations.

Even monster-battling princesses get tired sometimes! But a peaceful time away is hard to find as the humorousNew York Times best-selling series continues. What is the Bible really all about? Why was it written and can it be trusted? Why should we read it? In this revised edition of a classic work, John Stott answers these questions. With his usual clarity and authority he spells out the Bible's purpose, examines the social, geographical and historical background, and outlines the Bible's story line. He then guides readers to apply the Bible's teaching to their daily lives. This new edition contains new focus questions, charts, diagrams and indexes. Leon and the Place Between download PDF Everyone loves fresh flowers, and this book presents the finest details about how to grow them; how to cut them; how to care for them; how to preserve them and in fact the book is filled to the brim with all kinds of information that deals with every imaginable aspect of fresh cut flowers. Filled with illustrations and magnificent colour pictures; new ideas about fresh cut flowers; how to (or not to) handle fresh cut flowers; explanations, ideas, the history of fresh cut flowers, it's going to be a 'must have' for students of floristry, for florists, for garden buffs...in fact, for everyone who loves their garden and fresh flowers.

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